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. 2022 Jan 28;9:816144. doi: 10.3389/fcvm.2022.816144

Table 4.

Stratified analysis of associations between the WtHR and WC with all-cause mortality.

Subgroups WtHR WC
Tertile 1 Tertile 2 Tertile 3 P for trend P for interaction Tertile 1 Tertile 2 Tertile 3 P for trend P for interaction
Age group (years)
20–39 1.00 1.09
(0.59–2.01)
1.25
(0.56–2.82)
0.580 <0.001 1.00 1.06
(0.53–2.12)
1.58
(0.75–3.33)
0.190 <0.001
40–59 1.00 1.31
(1.01–1.70)
2.48
(1.66–3.68)
<0.001 1.00 1.17
(0.87–1.57)
1.77
(1.19–2.64)
0.004
≥60 1.00 1.19
(1.03–1.37)
1.74
(1.43–2.13)
<0.001 1.00 1.09
(0.96–1.25)
1.22
(1.02–1.47)
0.031
Sex
Men 1.00 1.40
(1.18–1.66)
2.37
(1.82–3.08)
<0.001 0.312 1.00 1.22
(1.01–1.47)
1.57
(1.23–2.01)
<0.001 0.507
Women 1.00 1.22
(1.03–1.45)
1.62
(1.29–2.04)
<0.001 1.00 1.09
(0.92–1.29)
1.25
(0.98–1.59)
0.070
Race/ethnicity
Hispanic 1.00 1.04
(0.77–1.40)
1.59
(1.04–2.44)
0.021 0.491 1.00 0.96
(0.75–1.21)
1.22
(0.86–1.72)
0.230 0.345
Non-Hispanic White 1.00 1.37
(1.17–1.60)
2.16
(1.74–2.68)
<0.001 1.00 1.18
(1.02–1.37)
1.42
(1.15–1.75)
0.001
Non-Hispanic Black 1.00 1.25
(0.93–1.68)
2.01
(1.35–3.00)
<0.001 1.00 1.23
(0.95–1.60)
1.43
(1.04–1.97)
0.030
Other race 1.00 0.88
(0.46–1.69)
0.71
(0.26–1.97)
0.525 1.00 0.85
(0.46–1.56)
1.06
(0.36–3.15)
0.951
Education
Grades 0–12 1.00 0.97
(0.81–1.16)
1.48
(1.13–1.94)
0.003 <0.001 1.00 1.00
(0.83–1.20)
1.16
(0.92–1.45)
0.199 0.002
High school/GED 1.00 1.45
(1.11–1.89)
2.52
(1.67–3.79)
<0.001 1.00 1.11
(0.83–1.47)
1.41
(0.97–2.05)
0.056
Some college or above 1.00 1.47
(1.21–1.80)
2.13
(1.63–2.77)
<0.001 1.00 1.32
(1.07–1.64)
1.70
(1.26–2.29)
<0.001
Marital status
Married 1.00 1.32
(1.09–1.59)
2.02
(1.57–2.60)
<0.001 0.635 1.00 1.21
(1.00–1.46)
1.51
(1.17–1.95)
0.001 0.349
Widowed/Divorced/Separated 1.00 1.15
(0.96–1.38)
1.77
(1.42–2.19)
<0.001 1.00 1.05
(0.88–1.25)
1.31
(1.01–1.70)
0.044
Never married 1.00 1.39
(0.84–2.29)
1.96
(0.91–4.21)
0.086 1.00 1.12
(0.66–1.88)
1.08
(0.56–2.09)
0.804
Living with partner 1.00 1.69
(0.90–3.17)
2.07
(0.81–5.34)
0.114 1.00 1.70
(0.93–3.10)
1.48
(0.57–3.88)
0.389
Body mass index category
Normal weight 1.00 1.18
(1.00–1.39)
1.66
(1.04–2.64)
0.021 0.308 1.00 1.20
(1.04–1.40)
0.86
(0.48–1.52)
0.034 0.197
Overweight 1.00 1.36
(1.07–1.74)
2.01
(1.53–2.63)
<0.001 1.00 1.09
(0.88–1.35)
1.24
(0.97–1.58)
0.046
Obesity 1.00 0.85
(0.11–6.45)
1.46
(0.20–10.81)
<0.001 1.00 0.49
(0.17–1.48)
0.68
(0.22–2.15)
0.023
Smoking status
Never 1.00 1.44
(1.19–1.73)
1.92
(1.54–2.39)
<0.001 0.849 1.00 1.13
(0.94–1.35)
1.28
(1.01–1.61)
0.036 0.197
Former 1.00 1.26
(1.04–1.53)
1.96
(1.49–2.59)
<0.001 1.00 1.30
(1.03–1.64)
1.60
(1.18–2.17)
0.003
Current 1.00 1.02
(0.75–1.39)
1.79
(1.09–2.95)
0.023 1.00 0.93
(0.68–2.26)
1.31
(0.80–2.14)
0.306
Alcohol intake
Lifetime abstainers 1.00 1.19
(0.97–1.47)
1.68
(1.26–2.23)
<0.001 0.263 1.00 1.05
(0.85–1.28)
1.26
(0.95–1.66)
0.098 0.484
Former drinker 1.00 1.41
(1.08–1.85)
2.06
(1.46–2.92)
<0.001 1.00 1.30
(0.99–1.70)
1.76
(1.18–2.60)
0.006
Light to moderate 1.00 1.26
(1.04–1.52)
1.97
(1.43–2.70)
<0.001 1.00 1.18
(0.96–1.45)
1.45
(1.08–1.96)
0.014
Heavy 1.00 1.27
(0.86–1.87)
2.14
(1.16–3.94)
0.016 1.00 0.94
(0.64–1.38)
0.90
(0.50–1.60)
0.705
Hypertension
Yes 1.00 1.18
(0.99–1.40)
1.68
(1.32–2.15)
<0.001 <0.001 1.00 1.08
(0.89–1.31)
1.26
(0.99–1.60)
0.046 0.001
No 1.00 1.30
(1.09–1.57)
2.20
(1.69–2.87)
<0.001 1.00 1.15
(0.99–1.34)
1.53
(1.21–1.93)
<0.001
Diabetes
Yes 1.00 0.77
(0.53–1.13)
1.02
(0.65–1.59)
0.571 0.120 1.00 1.12
(0.81–1.54)
1.22
(0.82–1.81)
0.318 0.838
No 1.00 1.39
(1.23–1.57)
2.20
(1.83–2.63)
<0.001 1.00 1.15
(1.01–1.31)
1.41
(1.14–1.74)
0.002
Heart disease
Yes 1.00 1.45
(1.17–1.80)
1.86
(1.39–2.50)
<0.001 0.245 1.00 1.48
(1.14–1.93)
1.51
(1.08–2.12)
0.032 0.434
No 1.00 1.24
(1.08–1.43)
2.00
(1.65–2.42)
<0.001 1.00 1.05
(0.92–1.20)
1.35
(1.09–1.68)
0.006
Stroke
Yes 1.00 1.29
(0.89–1.86)
1.35
(0.87–2.10)
0.209 0.033 1.00 1.23
(0.84–1.81)
1.22
(0.75–2.01)
0.473 0.195
No 1.00 1.29
(1.11–1.48)
2.05
(1.68–2.51)
<0.001 1.00 1.13
(0.98–1.30)
1.41
(0.17–1.71)
<0.001
Cancer
Yes 1.00 1.21
(0.96–1.52)
1.77
(1.30–2.41)
<0.001 0.009 1.00 1.11
(0.86–1.41)
1.08
(0.74–1.57)
0.698 <0.001
No 1.00 1.31
(1.12–1.53)
2.01
(1.62–2.49)
<0.001 1.00 1.16
(1.00–1.34)
1.50
(1.22–1.84)
<0.001

Values are weighted hazard ratio (95% confidence interval) unless stated otherwise.

WtHR, waist-to-height ratio; WC, waist circumference; GED, general equivalency diploma.

WtHR: Tertile 1, ≤ 0.54; Tertile 2, 0.55-0.62; Tertile 3, ≥0.63.

WC: Tertile 1, Men ≤ 0.93 cm, Women ≤ 0.88cm; Tertile 2, Men 0.94-1.05 cm, Women 0.89-1.02 cm; Tertile 3, Men ≥1.06cm, Women ≥1.03 cm.