Fig. 3.

Effects of CBD in pericytes (p4–6) exposed to 4-h OGD. a Effect of CBD (10 or 100 nM) on LDH concentrations 24 h following initiation of OGD (n = 6, from 2 separate experiments). Effect of various CBD samples (10 or 100 nM) on media IL-6 concentrations immediately after OGD (b), or 24 h following the initiation of OGD (c) (n = 6, from 2 separate experiments). Data are displayed as mean ± SEM % change from normoxic control and were compared for statistical significance against the normoxic control (#) or OGD vehicle (*) using a one-way ANOVA. *p ≤ 0.05, **p ≤ 0.01, and ***p ≤ 0.001. CBD, cannabidiol; OGD, oxygen glucose deprivation.