Table 4.

SOD2 and GPX3 Whole-Brain Analyses

	Cortical measure	Contrast	Peak cluster region	Size of cluster (mm2)	cwp	MNI X	MNI Y	MNI Z
SOD2 rs4880	Area	Interaction effect	rh paracentral gyrus	1815.84	0.008	11.9	−12.5	48.3
	Volume	Gene main effect	lh superior frontal gyrus	1114.53	0.004	−10.0	13.3	52.2
			rh caudal middle frontal gyrus	997.39	0.008	36.8	8.5	39.1
			rh superior temporal gyrus	774.06	0.040	56.3	3.3	−11.7
	Thickness	Gene main effect	rh superior temporal gyrus	1544.18	0.0001	52.1	−7.2	−13.1
GPX3 rs3792797	Area	Gene main effect	lh caudal middle frontal gyrus	1869.75	0.042	−36.5	13.5	33.7
			lh transverse temporal gyrus	1840.31	0.046	−51.6	−20.4	5.1
			rh rostral middle frontal gyrus	3633.70	0.0004	34.3	28.2	43.0
			rh postcentral gyrus	2417.59	0.009	47.3	−18.6	57.0
		Interaction effect	lh superior frontal gyrus	2839.21	0.002	−8.7	−7.2	57.7
			rh superior frontal gyrus	1991.16	0.028	20.2	24.4	45.6
	Volume	Gene main effect	lh postcentral gyrus	1598.50	0.006	−44.2	−23.3	56.0
			lh caudal middle frontal gyrus	1202.00	0.035	−36.6	17.8	49.8
			rh postcentral gyrus	1661.38	0.001	49.2	−21.1	56.6
		Interaction effect	rh supramarginal gyrus	1056.16	0.043	59.8	−37.8	21.8

Abbreviations: cwp, cluster wide P value; lh, left hemisphere; MNI, Montreal Neurological Institute; rh, right hemisphere.