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. 2021 Sep 17;25(2):106–117. doi: 10.1093/ijnp/pyab062

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© The Author(s) 2021. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Mean plasma concentration-time profiles of TP0178894 and TP0473292, and cerebrospinal fluid (CSF) concentration-time profiles of TP0178894 following a single oral administration of 100 mg TS-161 under fasted conditions. Figure is presented as the mean ± SD. Figure is presented as the mean +/- SD (n = 6).