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McLeod syndrome (MLS) and VPS13A disease (chorea-acanthocytosis) are phenotypically very similar neurohematological disorders. Certain features, such as cardiomyopathy or involuntary movements that interfere with chewing and swallowing (feeding dystonia), may be less common in one of the two, but presence of the Kell-McLeod phenotype (absence of Kx antigen) is the main distinguishing feature.
