Table 1.
Univariate and multivariate analysis of receiving first postoperative colonoscopy during 10–15 months after surgery for colon cancer (stage I-III) patients who had 3+ years follow up without recurrence after the surgery.
| Risk factor | Total n | Colonoscopy (10–15 m) |
No Colonoscopy (10–15 m) |
Unadjusted OR (95% CI) |
Adjusted OR (95% CI) |
||
|---|---|---|---|---|---|---|---|
| n | % | n | % | ||||
| Total n | 25573 | 12033 | 47% | 13540 | 53% | ||
| Age at diagnosis, (years) | p < 0.01 | p < 0.01 | |||||
| 65–74 (ref) | 9557 | 5667 | 59% | 3890 | 41% | – | – |
| 75–84 | 11715 | 5367 | 46% | 6348 | 54% | 0.58 (0.55–0.61) * | 0.64 (0.60–0.67) * |
| 85+ | 4301 | 999 | 23% | 3302 | 77% | 0.21 (0.19–0.23) * | 0.25 (0.23–0.28) * |
| Sex | p < 0.01 | p < 0.01 | |||||
| Female (ref) | 14997 | 6902 | 46% | 8095 | 54% | – | – |
| Male | 10576 | 5131 | 49% | 5445 | 51% | 1.11 (1.05–1.16) * | 0.85 (0.80–0.90) * |
| Year of diagnosis | p = 0.08 | p < 0.01 | |||||
| 2002–2004 (ref) | 9468 | 4396 | 46% | 5072 | 54% | – | – |
| 2005–2007 | 8719 | 4083 | 47% | 4636 | 53% | 1.02 (0.96–1.08) | 1.05 (0.98–1.11) |
| 2008–2011 | 7386 | 3554 | 48% | 3832 | 52% | 1.07 (1.01–1.14) * | 1.16 (1.08–1.24) * |
| Race | p < 0.01 | p < 0.01 | |||||
| Non-Hispanic white (ref) | 21319 | 10201 | 48% | 11118 | 52% | – | – |
| Non-Hispanic black | 1929 | 770 | 40% | 1159 | 60% | 0.72 (0.66–0.80) * | 0.75 (0.68–0.84) * |
| Hispanic | 1064 | 437 | 41% | 627 | 59% | 0.76 (0.67–0.86) * | 0.80 (0.70–0.92) * |
| Others | 1261 | 625 | 50% | 636 | 50% | 1.07 (0.96–1.20) | 1.14 (1.01–1.29) * |
| Region | p < 0.01 | p < 0.01 | |||||
| Eastern (ref) | 5594 | 2464 | 44% | 3130 | 56% | – | – |
| Midwest | 10829 | 5480 | 51% | 5349 | 49% | 1.30 (1.22–1.39) * | 1.16 (1.08–1.25) * |
| Western | 9150 | 4089 | 44% | 5061 | 55% | 1.03 (0.96–1.10) | 0.95 (0.89–1.02) |
| Neighborhood | p < 0.01 | p < 0.01 | |||||
| Large metropolitan (ref) | 13140 | 5828 | 44% | 7312 | 56% | – | – |
| Metropolitan | 7714 | 3776 | 49% | 3938 | 51% | 1.20 (1.14–1.27) * | 1.14 (1.07–1.21) * |
| Nonmetro urban/rural | 4719 | 2429 | 51% | 2290 | 49% | 1.33 (1.25–1.42) * | 1.23 (1.13–1.33) * |
| Marital status | p < 0.01 | p < 0.01 | |||||
| Single/divorced/widow (ref) | 11489 | 4547 | 40% | 6942 | 60% | – | – |
| Married/domestic partner | 13172 | 7090 | 54% | 6082 | 46% | 1.78 (1.69–1.87) * | 1.44 (1.36–1.53) * |
| Unknown | 912 | 396 | 43% | 516 | 57% | 1.17 (1.02–1.34) * | 1.08 (0.93–1.24) |
| SES rank § | p < 0.01 | p < 0.01 | |||||
| 1 (ref) | 4542 | 1949 | 43% | 2593 | 57% | – | – |
| 2 | 5413 | 2576 | 48% | 2837 | 52% | 1.21 (1.12–1.31) * | 1.20 (1.10–1.31) * |
| 3 | 3967 | 1898 | 48% | 2069 | 52% | 1.22 (1.12–1.33) * | 1.23 (1.12–1.35) * |
| 4 | 6606 | 3168 | 48% | 3438 | 52% | 1.23 (1.14–1.32)* | 1.31 (1.20–1.43) * |
| 5 | 5045 | 2442 | 48% | 2603 | 52% | 1.25 (1.15–1.35) * | 1.34 (1.22–1.48) * |
| Tumor location | p = 0.23 | p < 0.01 | |||||
| Right-sided colon (ref) | 17551 | 8303 | 47% | 9248 | 53% | – | – |
| Left-sided colon | 8022 | 3730 | 47% | 4292 | 54% | 0.97 (0.91–1.02) | 0.85 (0.81–0.91) * |
| Chemotherapy used | P<0.01 | P<0.01 | |||||
| No (ref) | 21662 | 9589 | 44% | 12073 | 56% | – | – |
| Yes | 3911 | 2444 | 62% | 1467 | 38% | 2.10 (1.96-2.25) * | 2.06 (1.88-2.24) * |
| Stage | p < 0.01 | p < 0.01 | |||||
| I (ref) | 8904 | 4480 | 50% | 4424 | 50% | – | – |
| II | 10909 | 4904 | 45% | 6005 | 55% | 0.86 (0.76–0.85) * | 0.82 (0.77–0.87) * |
| III | 5760 | 2649 | 46% | 3111 | 54% | 0.84 (0.79–0.90) * | 0.61 (0.56–0.66) * |
| Comorbidity (modified CCI) | P<0.01 | P<0.01 | |||||
| 0 (ref) | 13868 | 6996 | 50% | 6872 | 50% | – | – |
| 1 | 7132 | 3264 | 46% | 3868 | 54% | 0.83 (0.78–0.88) * | 0.86 (0.81–0.91) * |
| 2+ | 4573 | 1773 | 39% | 2800 | 61% | 0.62 (0.58–0.67) * | 0.68 (0.63–0.73) * |
Higher odds ratio (OR) indicates more likely to receive colonoscopy during 10–15 months after surgery of colon cancer.
*
Indicates significant at α = 0.05.
§
Higher SES rank indicates higher family income and education level.
CI, confidence interval; CCI, Charlson comorbidity index; SES, socioeconomic status.