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. Author manuscript; available in PMC: 2022 Feb 11.

Published in final edited form as: J Med Chem. 2020 Feb 26;63(6):3290–3297. doi: 10.1021/acs.jmedchem.9b02063

Figure 4. — Serum IgG (A), IgG1 (B), and IgG2a (C) anti-OVA response in mice immunized by the s.c. route with OVA alone or with GPI-0100 or a MS derivative. Mice were immunized on days 0, 14 and 28. Serum samples were collected prior to each immunization and at 6 weeks after the initial immunization. Values are expressed as mean ± SEM. Statistical significance in antibody responses was evaluated by t tests (with unpaired, nonparametric and Mann-Whiteny test). * P < 0.05 and ** P < 0.01 compared with mice immunized with OVA alone.

Figure 4. — Serum IgG (A), IgG1 (B), and IgG2a (C) anti-OVA response in mice immunized by the s.c. route with OVA alone or with GPI-0100 or a MS derivative. Mice were immunized on days 0, 14 and 28. Serum samples were collected prior to each immunization and at 6 weeks after the initial immunization. Values are expressed as mean ± SEM. Statistical significance in antibody responses was evaluated by t tests (with unpaired, nonparametric and Mann-Whiteny test). * P < 0.05 and ** P < 0.01 compared with mice immunized with OVA alone.