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Ratio of Serum anti-rHagB IgG2a and IgG1 activity (IgG2a/IgG1).Values are expressed as mean ± SD. Statistical significance compared with rHagB+VSA-2 (5b), Statistical significance was evaluated by t tests (with unpaired, nonparametric and Mann-Whiteny test). *P < 0.05, **P < 0.01.
