Table 1.

Pairwise multivariable analyses in the pediatric HL validation cohort

Variable	Patients		Pairwise multivariable analysis*
	No.	%	HR	SE	P
Pairwise analysis 1
Model score high	31	43.7	2.4	0.4	.017
Stage IV	15	21.1	1.3	0.4	.468
Pairwise analysis 2
Model score high	31	44.3	2.1	0.4	.055
Mediastinal mass >0.33†,‡	25	35.7	1.4	0.4	.401
Pairwise analysis 3
Model score high	31	43.7	3.0	0.4	.003
Fever	13	18.3	3.6	0.4	.002
Pairwise analysis 4
Model score high	29	43.3	2.3	0.4	.028
Albumin <3.5‡	19	28.4	2.6	0.4	.010
Pairwise analysis 5
Model score high	31	43.7	2.6	0.4	.010
Stratum SER	22	31.0	0.8	0.4	.620

HR, hazard ratio; SE, standard error; SER, slow early responder.

^*Pairwise multivariable analyses were performed with Cox proportional hazards regression models using only patients with data available for both variables.

^†Mediastinal mass was unavailable for 1 patient.

^‡Albumin measurements were unavailable for 4 patients.