Table 5.
Participants and session characteristics contributing to each set of longitudinal visits and variables
| Visit type | Variables involved | Total included visits (n) | Number of participants (n) | Between visit gap, month (mean±SD) | Number of visits (median (lower–upper quartile)) | Total person-time (months) |
|---|---|---|---|---|---|---|
| Clinical | CDR-SB/MMSE | 1316/1257 | 230 | 14.5±6.7 | 3 (2–5) | 9902 |
| Psychometric | PACC score | 1008 | 229 | 14.4±6.6 | 3 (2–5) | 25018 |
| MR session | AD cortical signature thickness/Total Hippocampal volume | 341/341 | 118 | 25.5±18.3 | 2 (1–3) | 14509 |
| WMH session | WMH volume | 214 | 83 | 30.6±16.8 | 2 (1–2) | 5210 |
| PIB/AV45 PET session | Centiloid | 102 | 46 | 40.8±21.3 | 2 (1–2) | 10699 |
Abbreviations: MMSE, Mini-Mental State Examination, CDR, Clinical Dementia Rating Scale, CDR-SB, Clinical Dementia Rating Scale Sum of Boxes, PACC, Preclinical Alzheimer Cognitive Composite, WMH, white matter hyperintensities, PIB, Pittsburgh compound B, AV45, 18F-AV45 (florbetapir), Centiloid, measure of global amyloid disposition based on the conversion of PIB or AV45 PET total cortical standardized uptake ratios to a standardized scale with arbitrary units ranging from 0 to 100, Total Hipp, total hippocampal volume, AD cortical signature thickness, cortical thickness in signature regions affected in Alzheimer disease