Table 1.
Contrast of the clinicopathology of LCC, LCNEC-null and LCNEC
| LCC | LCNEC-null | LCNEC | |
|---|---|---|---|
| (n = 7) | (n = 11) | (n = 13) | |
| Median age | 61 (41–68) | 64 (48–73) | 57 (42–78) |
| Sex | |||
| Male | 7 | 11 | 12 |
| Female | – | – | 1 |
| Smoking history | |||
| smoker | 7 | 8 | 12 |
| non-smoker | – | 3 | 1 |
| Tumour size (cm) | 7.5 ± 2.5 | 5.1 ± 3.2 | 6.8 ± 4.8 |
| Lymph node metastasis | 4 (57.1%) | 3 (27.3%) | 5 (38.5%) |
| Stage | |||
| I | – | 3 | 5 |
| II | 2 | 3 | 1 |
| III / IV | 5 | 5 | 7 |
| Pleural invasion | 3 (42.8%) | 3 (27.3%) | 6 (46.2%) |
| Color of cut surface | |||
| Yellow / Brown | 6 (85.7%) | 3 (27.3%) | 3 (23.0%) |
| White | 1 (14.3%) | 8 (72.7%) | 7 (53.8%) |
| Other | – | – | 3 (23.0%) |
| Tumour texture | |||
| Soft | 5 (71.4%) | – | – |
| Middle | 2 (28.6%) | 7 (63.6%) | 10 (76.9%) |
| Hard | – | 4 (36.4%) | 2 (15.4%) |
LCC, large cell carcinoma; LCNEC-null, large cell neuroendocrine carcinoma-null immunophenotype; LCNEC, large cell neuroendocrine carcinoma