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. 2022 Feb 11;22:115. doi: 10.1186/s12877-022-02793-2

Table 4.

Number and percent of individuals with multimorbitiy (i.e. at least two diseases) in each cluster

Cluster Total (1,667) Sex Birth phases
Male (788) Female (879) P-value Pre-war (370) Early war (561) Late war (176) Famine (310) After famine (250) P-value
Joint. Neuro. Anxiety. Depression 78 (4.7%) 22 (2.8%) 56 (6.4%)  < 0.001 26 (7%) 34 (6.1%) 2 (1.1%) 9 (2.9%) 7 (2.8%) 0.002
Heart. Stroke. Diabetes. Hypertension 818 (49.1%) 456 (57.9%) 362 (41.2%)  < 0.001 195 (52.7%) 258 (46%) 93 (52.8%) 156 (50.3%) 116 (46.4%)  < 0.001
Lung. Gastro. Kidney. Liver 106 (6.4%) 44 (5.6%) 62 (7.1%) 0.218 20 (5.4%) 31 (5.5%) 17 (9.7%) 19 (6.1%) 19 (7.6%) 0.051

P-value from Chi-square test for categorical variables. Phases were defined based on participant’s critical developmental age (prenatal gestation or the first two years of life) and the World War II situation in Germany