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. 2022 Feb 10;15:16. doi: 10.1186/s13041-022-00901-2

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Characterization of genetic generalized epilepsy in a marmoset family. a Pedigree of the epileptic marmoset family. b Seizure records of the epileptic marmosets involved in the study. c Time course of locomotion after PTZ injection. d Seizure scores in marmosets treated with PTZ. e Schematic diagram of EEG recording in marmosets. f, h Typical ECoG traces after handling in asymptomatic marmosets and epileptic marmosets. g, i Spectrogram corresponding to typical ECoG traces in asymptomatic marmosets and epileptic marmosets. j Main procedure of epileptiform spike detect modelling. k Number of detected epileptiform spikes during 10 h of free-roaming. Data are presented as mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001. P-value is determined by two-way ANOVA followed by Bonferroni's multiple comparisons test (c) or unpaired t-test (d, k)