Fig. 2.

Platelet transcriptome of COVID-19 patients. Total RNA from platelets of ICU and asymptomatic COVID-19 patients (n = 9 for each) was sequenced in Illumina HiSeq. (A) A heatmap generated from the list of differentially expressed transcripts showing a clear distinction between the platelet transcriptome from two groups. (B) Table shows some of the relevant pathways from total 211 pathways analysed from 598 differentially upregulated transcripts in ICU patients compared to asymptomatic. Rest of the pathways are described in Table S2. A similar list of 131 pathways from 676 downmodulated transcripts is described in Table S3. (C) Schematic represents the interaction network among the all gene transcripts described in pathways described in above Fig. B.

Platelet transcriptome of COVID-19 patients. Total RNA from platelets of ICU and asymptomatic COVID-19 patients (n = 9 for each) was sequenced in Illumina HiSeq. (A) A heatmap generated from the list of differentially expressed transcripts showing a clear distinction between the platelet transcriptome from two groups. (B) Table shows some of the relevant pathways from total 211 pathways analysed from 598 differentially upregulated transcripts in ICU patients compared to asymptomatic. Rest of the pathways are described in Table S2. A similar list of 131 pathways from 676 downmodulated transcripts is described in Table S3. (C) Schematic represents the interaction network among the all gene transcripts described in pathways described in above Fig. B.