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. 2022 Jan 28;13:806429. doi: 10.3389/fgene.2022.806429

TABLE 1.

Clinical characteristics of family members.

ID Sex AF onset (years) AF type Symptoms Comorbidities before AF diagnosis or within 1 year after Diagnostic Procedures Notes
II-1 F 57 Perm Palpitations none Echo: Normal
II-2 F NA NA NA HCL, obesity, HT, Diabetes NA No AF.
II-4 M 48 Perm Dyspnea HCL Echo: Arrhythmia induceret cardiomyopathy. Remission with control of AF.
II-5 M 47 Perm Unknown None Echo: Moderate pulmonary hypertension
II-6 M 40 Perm Presyncope, syncope HT Echo: Normal, CAG: Normal Difficulty to control AF - > His bundle ablation and pacemaker
III-1 M 37 Perm Dyspnea with activity obesity Echo: Marginally enlarged left atrium (73 ml)
III-2 M 38 Per Fatigue, dyspnea none Echo: Normal, CAG: Normal Aborted SCD. ICD
Flecanaid test: Negative, No sign of Brugada

HCL, Hypercholesteremia; HT, Hypertension; HF , Heart Failure; SCD, Sudden Cardiac Death; ICD, Implanted Cardioverter Defibrillator. Echo = Echocardiogram. CAG, Coronary Angiogram. M/F = Male/Female. Per. = Persistent. Perm = Permanent.