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Knockout of Nrf2 abolished the protective capability of Daph for ovarian function and follicular development. (A,B) The serum FSH and E2 levels were tested in the five groups in Nrf2−/− mice. (C,D) GSH and SOD expression in ovarian tissues was tested. (E) Follicles were observed after H&E staining. (F) Summarizing the numbers of follicles at different developmental stages. All data are shown as means ± SEMs, n = 5. Statistical significance: **p < 0.01.
