TABLE 2.

Daph’ effect in Nrf2 Knockout mice.

Parameters	Control group	D-gal (600 mg/kg/d) group	D-gal + Daph (15 mg/kg/d) group	D-gal + Daph (30 mg/kg/d) group	D-gal + VE (30 mg/kg/d)Group
FSH (mIU/ml)	11.310 ± 0.481	16.594 ± 0.546	16.062 ± 0.411	15.920 ± 0.341	15.726 ± 0.308
E2 (pg/ml)	9.944 ± 0.265	6.702 ± 0.360	7.018 ± 0.395	6.814 ± 0.462	7.566 ± 0.319
GSH (umol/L)	47.224 ± 3.012	27.190 ± 1.557	28.870 ± 1.960	30.828 ± 1.705	31.542 ± 1.900
SOD (U/mgprot)	16.056 ± 0.447	9.464 ± 0.714	10.224 ± 0.576	10.632 ± 0.539	11.116 ± 0.540
P16 a	0.998 ± 0.252	2.088 ± 0.157	2.034 ± 0.165	2.083 ± 0.251	2.023 ± 0.150
Klotho a	0.316 ± 0.014	0.232 ± 0.002	0.226 ± 0.003	0.232 ± 0.013	0.238 ± 0.014
Nrf2 a	0.138 ± 0.027	0.042 ± 0.005	0.041 ± 0.003	0.045 ± 0.005	—
NQO1 a	0.148 ± 0.030	0.045 ± 0.005	0.042 ± 0.003	0.047 ± 0.006	—
HO-1 a	0.135 ± 0.025	0.042 ± 0.003	0.42 ± 0.002	0.046 ± 0.005	—
TXNIP (IOD/Aera)	0.100 ± 0.006	0.271 ± 0.010	0.271 ± 0.008	0.267 ± 0.010	0.260 ± 0.009
NLRP3 (IOD/Aera)	0.090 ± 0.020	0.284 ± 0.006	0.283 ± 0.012	0.288 ± 0.007	0.290 ± 0.011

^a: Relative protein level of β-actin.