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. 2022 Feb 3;119(6):e2111711119. doi: 10.1073/pnas.2111711119

Fig. 6.

Fig. 6.

The Yun/PHB complex acts through E2F1. (A) Cell cycle arrests in upon yun/Phb depletion. (A4) Quantification of the percentage of cells per frame. n = 20. (B) The levels of E2F1 are significantly diminished upon yun/Phb depletion. (B4) Quantification of the IOD of E2F1. Mean ± SD is shown. n ≥ 50. ***P < 0.001. (B5 to B7) The Yun/PHB complex associates with E2F1 in vivo. (C) E2F1 acts downstream of the Yun/PHB complex. (C5) Quantification of the number of pH3. Mean ± SD is shown. ***P < 0.001. (C11) Quantification of the clone size. Mean ± SD is shown. ***P < 0.001 [Scale bars, 20 μm (A and C) and 10 μm (B)].