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. 2022 Jan 19;14(2):789–799. doi: 10.18632/aging.203840

Table 2. Univariate and multivariate logistic regression analyses of prognostic factors in patients with prolonged DOC in training set.

Variable Univariate Multivariate
OR(95%CI) P-value OR(95%CI) P-value
Age(years) 1.041(1.016-1.069) 0.002 1.037(1.006-1.071) 0.022
Sex
Female Ref
Male 0.978(0.478-2.001) 0.952
Etiology
Trauma 1.099(0.552-2.186) 0.788
Stroke Ref
Anoxia 1.389(0.329-5.864) 0.654
CRS-R total score 0.834(0.748-0.923) 0.006 1.073(0.895-1.294) 0.399
GCS total score 0.612(0.473-0.768) 0.005 0.699(0.499-0.947) 0.027
Serum albumin(g/L) 0.921(0.844-1.001) 0.560
Hemoglobin(g/L) 0.990(0.969-1.011) 0.356
Basic cardiopulmonary diseases
Presence Ref
Absence 0.517(0.160-1.672) 0.264
Level of consciousness
VS Ref Ref
MCS 0.202(0.096-0.410) 0.000 0.309(0.087-1.039) 0.043
Multiple injuries
Presence Ref
Absence 1.237(0.580-2.639) 0.581
EEG background activity
Alpha rhythms exists Ref Ref
Lack of alpha rhythms 4.216(2.047-8.686) 0.000 2.252(0.958-5.428) 0.065
N20 on SEP
Presence Ref Ref
One or both absent 10.02(2.282-44.075) 0.000 3.24(0.712-23.580) 0.168
BAEP grade
GradeI-II Ref Ref
GradeIII-IV 4.987(2.395-11.010) 0.000 2.779(1.150-7.024) 0.026
Midline shift
Presence Ref
Absence 0.474(0.148-1.521) 0.202
Hypertension
Presence Ref
Absence 0.978(0.478-2.001) 0.952
Smoking history
Presence Ref
Absence 0.605(0.205-1.782) 0.358
Cholesterol
>5.17mmol/L Ref
≤5.17mmol/L 0.798(0.262-2.430) 0.690
Triglyceride
>1.70mmol/L Ref
≤1.70mmol/L 1.650(0.816-3.338) 0.162