Fig. 7.

Decay of 2LTR circles in circulating CD4⁺ T cells. The 2LTR circles (red circles) were measured by duplex digital droplet PCR as droplets with fluorescent signal for the both the circle junction and env amplicons (SI Appendix, Fig. S3 A and B). Intact provirus measurements (blue squares) for the same samples are shown for comparison. Data are show for participants for whom samples were obtained throughout the first year of ART. Circles could not be measured for participant 448 due to circle junction polymorphisms.