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. 2022 Jan 28;9:807712. doi: 10.3389/fped.2021.807712

Table 3.

Main neonatal diagnosis at term equivalent age.

24 h-IB Bolus-IB P -value
(n = 70) (n = 76)
Mortality n (%) 1 (1.4) 6 (8) 0.1
NEC or SIP, n (%) 7 (10) 2 (2.6) 0.1
Combined outcome: mortality or NEC or SIP, n (%) 8 (11.4) 7 (9.2) 0.8
Normal CUS or IVH grade I, n (%) 41 (59) 24 (33) 0.4
IVH grade II or III, n (%) 8 (11) 14 (19) 0.3
PVIH, n (%) 1 (1.4) 3 (4.1) 0.6
White matter damage, n (%) 16 (23) 18 (25) 0.9
Cerebellum injury, n (%) 1 (1.4) 4 (5.4) 0.4
Full enteral feeds, days (median, IQR) 19.5 (12.2–28.7) 14 (10–25) 0.03
PDA reopening after confirmed closed, n (%) 7 (10) 7 (9) 1
Surgical closure of PDA, n (%), n (%) 22 (31) 16 (21) 0.2
O2 dependency at 36 weeks, n (%) 39 (56) 42 (60) 0.8
ROP treatment, n (%) 16 (32) 10 (14) 0.8
Age at discharge, days (median, IQR) 88 (68–104) 85.5 (58–99) 0.12

NEC, necrotising enterocolitis; SIP, spontaneous intestinal perforation; CUS, cranial ultrasound; IVH, intraventricular hemorrhage; PVIH, periventricular hemorrhagic infarction; PDA, patent ductus arteriosus; ROP, retinopathy of prematurity.