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. 2022 Jan 24;119(6):e2120419119. doi: 10.1073/pnas.2120419119

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Copyright © 2022 the Author(s). Published by PNAS.

This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY).

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Fig. 4. — Redox-sensitive, redox-modified, and hyperreactive cysteines in SARS-CoV-2 RBD. (A) Workflow for identifying redox-sensitive cysteines in recombinant RBD of SARS-CoV-2 spike. (B) Redox-sensitive cysteines in recombinant RBD. Redox-sensitive and unmodified/unidentified sites are denoted by colored and gray boxes, respectively. (C) Workflow for identifying redox-modified and hyperreactive cysteines in in recombinant RBD. (D) Redox-modified and hyperreactive cysteines in recombinant RBD. Redox-modified, hyperreactive, and unmodified/unidentified sites are denoted by blue, pink, and gray boxes, respectively (workflow depicted in SI Appendix, Fig. S3 C and D).