Table 2. Go and KEGG analysis of the five top CTS-related genes.

Ontology	ID	Description	GeneRatio	p adjust	q Value
BP	GO:0042119	Neutrophil activation	23/60	6.83E−18	4.09E−18
BP	GO:0043312	Neutrophil degranulation	21/60	7.49E−16	4.48E−16
BP	GO:0002283	Neutrophil activation involved in immune response	21/60	7.49E−16	4.48E−16
BP	GO:0002446	Neutrophil mediated immunity	21/60	8.86E−16	5.3E−16
BP	GO:0006909	Phagocytosis	17/60	5.07E−13	3.03E−13
CC	GO:0030139	Endocytic vesicle	13/61	1.11E−09	5.08E−10
CC	GO:0070820	Tertiary granule	10/61	4.05E−09	1.86E-09
CC	GO:0030666	Endocytic vesicle membrane	10/61	4.05E−09	1.86E−09
CC	GO:0030667	Secretory granule membrane	12/61	4.05E−09	1.86E−09
CC	GO:0042613	MHC class II protein complex	5/61	3.22E−08	1.48E−08
MF	GO:0001540	Amyloid-beta binding	9/58	6.6E−10	4.7E−10
MF	GO:0042277	Peptide binding	12/58	1.57E−08	1.12E−08
MF	GO:0033218	Amide binding	12/58	8.93E−08	6.37E−08
MF	GO:0008329	Signaling pattern recognition receptor activity	4/58	0.0000225	0.0000161
MF	GO:0038187	Pattern recognition receptor activity	4/58	2.25E−05	0.0000161
KEGG	hsa04145	Phagosome	15/51	1.19E−12	6.15E−13
KEGG	hsa05150	Staphylococcus aureus infection	12/51	2.18E−11	1.12E−11
KEGG	hsa05140	Leishmaniasis	11/51	3.37E−11	1.74E−11
KEGG	hsa05152	Tuberculosis	13/51	1.26E−09	6.5E−10
KEGG	hsa05133	Pertussis	9/51	1.61E−08	8.3E−09

Note:

BP: biological process, GO: gene ontology, KEGG: Kyoto Encyclopedia of Genes and Genomes.