Table 1.

Inclusion and exclusion criteria.

Inclusion Criteria	Exclusion Criteria
IBD patients with incident CRC occurring during our 6-year study [25] with additional data not previously reported	Incomplete data regarding the CRC characteristics and/or clinical outcome of IBD patients with incident CRC after the end of the first study (31 December 2017)
Diagnosis of CD or UC according to current European guidelines [26,27]	Patients from the previous cohort [25] with incident cancer different from CRC
Well-defined diagnosis of incident CRC (31 December 2011–31 December 2017) [25]	All IBD controls with no cancer included in our previous study [25]
Detailed clinical data regarding IBD and CRC, including the clinical outcome of CRC after the end of our first study (31 December 2017) [25]	Low compliance (<2 visits/year)
Diagnosis of IBD lasting ≥6 months
Regular follow up (≥2 visits/year)
Age ≥ 17 years
Well-defined characteristics of CRC including: Histotype, Site, CRC treatment (surgery, chemo/radiotherapy), Diagnostic modalities of CRC, Personal history of adenomas
Well-defined characteristics of CRC including: Histotype, Site, CRC treatment (surgery, chemo/radiotherapy), Diagnostic modalities of CRC, Personal history of adenomas

Abbreviations. IBD: Inflammatory Bowel Disease; UC: Ulcerative Colitis; CD: Crohn’s Disease; CRC: colorectal cancer.