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. 2022 Jan 27;14(3):644. doi: 10.3390/cancers14030644

Figure 3.

Figure 3

Illustration of the implications of meaningful clinical read out selection for establishing the potential additive versus synergistic effects of anti-VEGF and CPI therapies. Kaplan–Meier curves showing (vs. black reference group) a continued drop off (a) versus a plateau (b) and waterfall plots (c,d) with differing shoulders but the same median. CPI, checkpoint inhibitor; VEGF, vascular endothelial growth factor.