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. 2022 Jan 31;14(3):739. doi: 10.3390/cancers14030739

Figure 6.

Figure 6

PRCPi decreases tyrosine phosphorylation of RTKs and IRS1. MDA468 cells (top panel) and SUM159PT cells (bottom panel) were serum-starved overnight and then treated with EGF (50 ng/mL), Heregulin b1 (HRG, 50 ng/mL), insulin (INS, 50 ng/mL), or PDGF-BB (50 ng/mL) for 10 min. Lysates were immunoblotted. Original Western Blots and densitometry can be found at Figures S10 and S11.