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. 2022 Jan 18;12(3):223. doi: 10.3390/ani12030223

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Changes in leukogram and CD4⁺/CD8⁺ ratio at 4 different times. Change in white blood cell count (A), where the 1st week was significantly different from the 2nd, 3rd, and 4th inductions (p = 0.0075, p = <0.0001, and p = 0.0271, respectively); Change in neutrophil count (B), where the 1st induction was significantly different from the 2nd and 3rd inductions (p = 0.0179, and p < 0.0001, respectively); Change in lymphocyte count (C), with no significant differences among the 4 times (p = 0.0965); Change in CD4⁺/CD8⁺ ratio (D) among 4 times, with no significant differences (p = 0.7407). The shaded part is the normal reference range.