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. 2022 Jan 29;14(3):691. doi: 10.3390/cancers14030691

Figure 2.

Figure 2

Fecal microbiota transplant restores intestinal microbial composition to modulate the adaptive immune responses, re-establish intestinal microbial homeostasis, and alter the host metabolism. Short chain fatty acids such as butyrate and propionate interact with G-protein coupled receptors GPR-43/41 on L cells to produce glucagon-like peptide 1 (GLP-1) and peptide YY (PYY), which contributes to reducing food intake and improving glucose metabolism [17].