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. 2022 Jan 29;14(3):691. doi: 10.3390/cancers14030691

Table 2.

Reported results of FMT for corticosteroid-refractory GVHD.

Reference Data Source Number of Patients (n) Outcome Adverse Events
Kakihana et al. [58] Single center prospective study 4 (received a total of 7 FMT by nasogastric administration) 3 CR and 1 PR 1 case of lower gastrointestinal bleed and hypoxemia, may not be related to FMT
Spindelboeck et al. [59] Retrospective case series 3 (received a total of 9 FMT by colonoscopy) 2 CR and 1 PR None reported
Qi et al. [60] Single center prospective study 8 (received a total of 12 FMT by nasogastric administration) 5 CR and 1 PR None reported
Shouval et al. [61] Single center prospective study 7 (received a total of 15 FMT by capsule administration) 2 CR 2 episodes of bacteremia, deemed unrelated to FMT
van Lier et al. [62] Single center prospective study 15 (received a total of 15 FMT by nasoduodenal tube administration) 10 CR None reported
Zhao et al. [63] Single center open-label Phase I/II study 41 (23 assigned to FMT and 18 to control. FMT administered by nasojejunal or gastric tube) Overall response rate of 82.6% (52.2% CR and 30.4% PR) in the FMT group and 39% (all PR) in the control group on Day 14 after FMT, and an overall response rate of 69.5% (56.5% CR and 13% PR) in the FMT group and 50% (16% CR and 34% PR) in the control group on Day 21 after FMT No difference in the adverse events between the FMT group and the control group.
Goeser et al. [64] Two-center retrospective study 11 (9 by capsule and 2 by nasojejunal tube administration) Attenuation of stool volume and frequency was observed in all 11 patients Abdominal pain occurred in 3 patients and vomiting in 1 patient
Mao et al. [65] Case report 1 (received two cycles of FMT administered by capsules) CR None reported