Kakihana et al. [58] |
Single center prospective study |
4 (received a total of 7 FMT by nasogastric administration) |
3 CR and 1 PR |
1 case of lower gastrointestinal bleed and hypoxemia, may not be related to FMT |
Spindelboeck et al. [59] |
Retrospective case series |
3 (received a total of 9 FMT by colonoscopy) |
2 CR and 1 PR |
None reported |
Qi et al. [60] |
Single center prospective study |
8 (received a total of 12 FMT by nasogastric administration) |
5 CR and 1 PR |
None reported |
Shouval et al. [61] |
Single center prospective study |
7 (received a total of 15 FMT by capsule administration) |
2 CR |
2 episodes of bacteremia, deemed unrelated to FMT |
van Lier et al. [62] |
Single center prospective study |
15 (received a total of 15 FMT by nasoduodenal tube administration) |
10 CR |
None reported |
Zhao et al. [63] |
Single center open-label Phase I/II study |
41 (23 assigned to FMT and 18 to control. FMT administered by nasojejunal or gastric tube) |
Overall response rate of 82.6% (52.2% CR and 30.4% PR) in the FMT group and 39% (all PR) in the control group on Day 14 after FMT, and an overall response rate of 69.5% (56.5% CR and 13% PR) in the FMT group and 50% (16% CR and 34% PR) in the control group on Day 21 after FMT |
No difference in the adverse events between the FMT group and the control group. |
Goeser et al. [64] |
Two-center retrospective study |
11 (9 by capsule and 2 by nasojejunal tube administration) |
Attenuation of stool volume and frequency was observed in all 11 patients |
Abdominal pain occurred in 3 patients and vomiting in 1 patient |
Mao et al. [65] |
Case report |
1 (received two cycles of FMT administered by capsules) |
CR |
None reported |