Table A3.
Search terms and search strategy in Cochrane Central Register of Controlled Trials.
| Domain | No. | Search Terms | Limits |
|---|---|---|---|
| P 1 | #1 | “breast cancer” OR “breast neoplasm” | In Trials |
| P 2 | #2 | “human epidermal growth factor receptor 2” OR “HER 2” | |
| #3 | “erbB2” | ||
| #4 | #2 OR #3 | ||
| P | #5 | P1 AND P2 #1 AND #4 |
In Trials |
| I 1 | #6 | “neoadjuvant” | In Trials |
| #7 | “preoperative” | ||
| #8 | #6 OR #7 | ||
| I 2 | #9 | “anti HER2” | |
| #10 | “anti human epidermal growth factor receptor 2” | ||
| #11 | “targeted therapy” | ||
| #12 | “trastuzumab” OR “Herceptin” | ||
| #13 | “pertuzumab” OR “perjeta” | ||
| #14 | “lapatinib” OR “Tykerb” | ||
| #15 | #9 OR #10 OR #11 OR #12 OR #13 OR #14 | ||
| I | #16 | I 1 OR I 2 #8 OR #15 |
In Trials |
| O 1 | #17 | “complete response” | In Trials |
| O 2 | #18 | “survival” | |
| O 3 | #19 | “adverse event” | |
| O | #20 | O1 OR O2 OR O3 #17 OR #18 OR #19 |
In Trials |
| Combination | |||
| P, I, O | - | #5 AND #16 AND #20 | In Trials |