Table 5.
Excess relative risks various primary glaucoma type incidence in relation to cumulative brain absorbed dose of external gamma-ray exposure lagged for 5 years—modification effects.
| Analysis | ERR/Gy (95%CI) | |||
|---|---|---|---|---|
| POAG | HTG | NTG | PACG | |
| Sensitivity analysis: the dataset restricted to certain groups of workers | ||||
| Sex | ||||
| Males | 0.06 (−0.11, 0.31) | −0.002 (−0.19, 0.26) | 0.31 (−0.20, 1.40) | 0.09 (−0.58, 3.07) |
| Females | 0.12 (−0.19, 0.59) | −0.04 (−0.33, 0.38) | 1.47 (0.007, 8.91) | −0.07 (n/a, 3.05) |
| p 1 | p > 0.5 | p > 0.5 | p = 0.27 | p > 0.5 |
| Attained age, years | ||||
| <50 | 0.12 (−0.70, 9.51) | 0.003 (−0.67, 7.40) | 11.97 (−14.56, 1382) | 25.73 (n/a, 41,300) |
| 50−59 | −0.04 (−0.45, 0.74) | −0.15 (n/a, 0.57) | 0.78 (−0.74, 13.09) | −0.18 (n/a, 1.16) |
| 60−69 | 0.14 (−0.09, 0.53) | 0.05 (−0.21, 0.47) | 0.41 (−0.20, 1.82) | −0.18 (n/a, −0.28) |
| ≥70 | 0.03 (−0.20, 0.36) | −0.03 (−0.25, 0.28) | 0.71 (−0.28, 5.49) | 3.2 (−3.13, 80.27) |
| p 2 | p > 0.5 | p > 0.5 | p > 0.5 | p = 0.29 |
| p 3 | p > 0.5 | p > 0.5 | p = 0.20 | p > 0.5 |
| Age at hire, years | ||||
| <30 | 0.02 (−0.12, 0.24) | −0.0 (−0.22, 0.15) | 0.40 (−0.06, 1.51) | 0.13 (−0.57, 2.83) |
| 30−39 | −0.20 (n/a, 0.38) | −0.15 (n/a, 0.80) | −0.20 (n/a. 0.45) | −0.20 (n/a, 19.31) |
| ≥40 | 7.85 (n/a, 73.89) | 5.14 (−3.28, 49.85) | 413,000 (n/a, 53,280,000) | −0.20 (n/a, 143.8) |
| p 4 | p = 0.23 | p = 0.17 | p = 0.42 | p > 0.5 |
1 p value in a test for heterogeneity between males and females, 2 p value in a test for heterogeneity among groups of workers by attained age based on the likelihood criteria, 3 p value in a test for non-linear trend in ERR/Gy by attained age based on likelihood criteria, 4 p value in a test for heterogeneity among group of workers by age at hire based on likelihood criteria; CI, confidence interval; ERR/Gy, excess relative risk per unit absorbed dose; Gy, gray; n/a, not available; POAG, primary open-angle glaucoma; HTG, high-tension glaucoma; NTG, normal-tension glaucoma; PACG, primary angle-closure glaucoma. Estimates in bold are statistically significant.