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. 2022 Jan 29;14(3):694. doi: 10.3390/cancers14030694
(m)UC (Metastatic) urothelial carcinoma
(N)MIBC (Non-)muscle-invasive bladder cancer
AEs Adverse events
≥G3 AE ≥Grade 3 adverse event
irAE Immune-related adverse event
sAE Serious adverse event
APC Antigen-presenting cells
ASCO-GU Genitourinary Cancers Symposium of the American Society of Clinical Oncology
AUA American Urologic Association
BC Bladder cancer
BCG Bacille Calmette–Guérin
BPS Bladder-preserving strategies
CEA Carcinoembryonic antigen
CIS Carcinoma in situ
ClTr Clinical trials
CPI Checkpoint inhibition
CPS Combined positive score
CR Complete response
CT Center of the tumor
CUETO Club Urologico Español deTratamiento Oncologico
DDM Dodecyl maltoside
DoR Duration of response
EAU European Association of Urology
EBRT External Beam Radiotherapy of the Bladder
ECOG Eastern Cooperative Oncology Group
EFS Event-free survival
EORTC European Organisation for Research and Treatment of Cancer
FDA United States Food and Drug Administration
FoxP3 Forkhead box protein P3
FU Follow up
G1–3 Grading 1–3
LG Low grade
HG High grade
GM-CSF Granulocyte-macrophage colony-stimulating factor
HG-RFS High-grade recurrence-free survival
I Immunoscore
i.v. Intravenously
iCT Intravesical chemotherapy
IFN Interferon
IL Interleukin
IM Invasive margin
Maint. Maintenance
MDSC Myeloid-derived suppressor cells
MHC Major histocompatibility complex
MMC Mitomycin C
MUC Antigens epithelial mucin 1
n.a. Not applicable
NA Not available
NKT-cell Natural killer T-cell
OM Oportuzumab monatox
PD Progressive disease
PD-(L)1 Programmed cell death (ligand)-1
PRISMA Preferred Reporting Items for Systematic Review and Meta-Analysis statement
Rb Retinoblastom
rBCG Repeat BCG
RC Radical cystectomy
RCT Randomized controlled trial
RECIST Response evaluation criteria in solid tumors
RR Risk ratio
SD Stable disease
TAM Tumor-associated macrophage
TIL Tumor-infiltrating lymphocyte
TLR Toll-like receptor
TMB Tumor mutational burden
TU Tumor
TURBT Transurethral resection of bladder tumor
UTI Urinary tract infection
Vp Viral particles
WHO World Health Organization