. 2022 Jan 30;14(3):732. doi: 10.3390/cancers14030732

Table 3.

Lipid composition and application of lung cancer exosomes.

Lipid		Source		Application ^b	Year [Ref]
Marker	Lung Cancer	Cell Line	Biopsy	Application ^b	Year [Ref]
-	16 lipid features ^b: PC(18:1_18:2), PC(18:0_18:2), PC(16:0_22:6), PC(16:0_18:2), SM(d18:1_16:0), PC(18:0_20:3), PC(16:0_20:4), PC(16:0_22:5), CE(20:4), TAG(52:5), SM(d18:1_24:1), PC(18:0_18:1), PC(16:0_16:0), TAG(54:6), LysoPC(16:0), LysoPC–pmg(12:0)	-	Plasma (NSCLC I, II) Plasma (NSCLC III, IV)	Diagnosis	2018 [195]

^a Classification models were built on the basis of lipid features (monoisotopic accurate m/z values). The assigned lipid names were listed. ^b Please refer to the section “Lipid composition and function of lung cancer exosomes” and original papers for marker usage. Abbreviations: NSCLC: non-small-cell lung cancer; CE: cholesterol ester; LysoPC: lysophosphatidylcholine; LysoPC–pmg: lysophosphatidylcholine-plasmalogen; PC: phosphatidylcholine; SM: sphingomyelin; TAG: triacylglyceride.