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Several modifiable and non-modifiable factors influence the epigenome in cancers, which can then be explored to determine diagnostic and prognostic aspects, measuring epigenetic biomarkers from tissue specimens or bodily fluids (lncRNA = long non-coding RNAs, 5mdC/5hmdC = 5-methyl or 5-hydroxymethyldeoxycytidine, miRNA = microRNA, circRNA = circular RNA).
