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. 2022 Feb 7;12(3):391. doi: 10.3390/ani12030391

Table 1.

The top 50 up-regulated skim milk proteins in HL yaks.

No. NCBInr Accession NCBInr Description Mass
(kDa)
Protein Coverage (%) Fold
Change *
1 gi|440897559 14-3-3 protein theta, partial 29.1 11.7 10
2 gi|440898761 Spliceosome RNA helicase BAT1 50.5 5.5 6.82
3 gi|440897815 Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48 kDa subunit, partial 50.8 2.4 6.49
4 gi|440892840 Small nuclear ribonucleoprotein-associated protein N, partial 24.7 3.3 5.73
5 gi|440892885 Protein S100-A1, partial 13.9 11.9 5.56
6 gi|440896162 Tubulin beta-7 chain 50.1 28.6 5.35
7 gi|15718687 40S ribosomal protein S3 isoform 1 26.8 3.7 5.13
8 gi|115498012 Glycogen phosphorylase, liver form 88.3 3.4 4.87
9 gi|440895215 Hemoglobin subunit beta, partial 18.0 38.3 4.64
10 gi|440906467 D-3-phosphoglycerate dehydrogenase 56.8 8.1 4.6
11 gi|440905390 Haptoglobin, partial 45.5 4.3 4.21
12 gi|440907809 Annexin A4, partial 36.1 25.4 4.21
13 gi|32189334 ADP/ATP translocase 2 33.1 10.1 3.90
14 gi|326933110 PREDICTED: histone-binding protein RBBP4-like 47.3 1.9 3.88
15 gi|440895216 Hemoglobin subunit epsilon-1, partial 16.5 23.8 3.87
16 gi|7106387 Proteasome subunit alpha type-5 25.4 5.2 3.79
17 gi|440912614 Annexin A1 39.2 3.8 3.69
18 gi|440903260 Keratin, type I cytoskeletal 42 51.5 5.6 3.58
19 gi|440901472 Secretoglobin family 1D member 2 11.5 8.8 3.45
20 gi|440900805 Sodium/potassium-transporting ATPase subunit alpha-1, partial 115.9 2.6 3.42
21 gi|440907817 Hypothetical protein M91_09610 27.6 4.9 3.4
22 gi|440903642 T-complex protein 1 subunit gamma, partial 64.1 1.9 3.28
23 gi|62460420 Heterogeneousnuclear ribonucleoprotein F 46.0 4.1 3.1
24 gi|440899875 Signal transducer and activator of transcription 1, partial 89.1 1.4 3.06
25 gi|351702463 Calponin-3 19.7 6.2 3.03
26 gi|440902212 Adenosylhomocysteinase, partial 47.5 1.9 2.97
27 gi|444513904 Heterogeneous nuclear ribonucleoprotein A1, partial 20.6 23.9 2.95
28 gi|440902100 Heterogeneous nuclear ribonucleoprotein C 33.8 7.5 2.79
29 gi|73955372 PREDICTED: profilin-1-like 10.5 40.6 2.77
30 gi|440908857 Clathrin heavy chain 1, partial 191.6 5.5 2.76
31 gi|195157178 GL12416 50.8 42.6 2.75
32 gi|440900693 Keratin, type II cytoskeletal 8, partial 54.4 14.8 2.75
33 gi|440901320 Synaptophysin-like protein 1 28.3 4.3 2.69
34 gi|4504447 Heterogeneousnuclear ribonucleoproteins A2/B1 isoform A2 35.8 24.2 2.66
35 gi|115495959 ATP-dependent RNA helicase DDX1 83.1 1.5 2.62
36 gi|440900692 Keratin, type I cytoskeletal 18, partial 49.2 5.0 2.5
37 gi|440900744 Alpha-S2-casein, partial 25.7 21.5 2.48
38 gi|440909809 Hypothetical protein M91_11302, partial 50.1 20.7 2.48
39 gi|344290140 PREDICTED: eukaryotic translation initiation factor 5A-1-like 17.3 7.6 2.45
40 gi|331284195 Nucleolin 77.2 2.0 2.45
41 gi|431895946 NMDA receptor-regulated protein 2 39.3 30.9 2.44
42 gi|114051505 Serpin H1 precursor 46.6 19.9 2.44
43 gi|440899031 Heat shock protein HSP 90-alpha, partial 37.7 29.1 2.36
44 gi|4505585 Platelet-activating factor acetylhydrolase IB subunit beta isoform a 25.7 3.9 2.36
45 gi|440900746 Alpha-S1-casein, partial 24.5 91.6 2.35
46 gi|440908101 L-lactate dehydrogenase B chain 37.4 13.6 2.33
47 gi|440895669 Triosephosphate isomerase 30.9 12.9 2.31
48 gi|440900959 60S ribosomal protein L12, partial 21.2 7.8 2.26
49 gi|78369302 Catalase 60.1 3.0 2.21
50 gi|440904790 Annexin A6, partial 75.7 7.9 2.18

* Relative abundance of proteins in HL yak milk versus TL yak milk.