Table 2.
The top 50 down-regulated skim milk proteins of HL yaks.
| No. | NCBInr Accession | NCBInr Description | Mass (kDa) |
Protein Coverage (%) | Fold Change * |
|---|---|---|---|---|---|
| 1 | gi|440897611 | 6-phosphofructokinase, muscle type | 94.3 | 2.8 | 0.1 |
| 2 | gi|311257294 | PREDICTED: cytochrome b-c1 complex subunit Rieske, mitochondrial-like | 29.8 | 2.6 | 0.1 |
| 3 | gi|440913466 | Hemoglobin subunit alpha-1, partial | 16.4 | 6.0 | 0.12 |
| 4 | gi|440904354 | Cytochrome c1, heme protein, mitochondrial, partial | 31.5 | 4.9 | 0.14 |
| 5 | gi|440893900 | Primary amine oxidase, liver isozyme, partial | 86.9 | 1.3 | 0.17 |
| 6 | gi|410964723 | PREDICTED: integrin alpha-7 isoform 2 | 129.1 | 1.0 | 0.21 |
| 7 | gi|110350683 | Biglycan precursor | 41.9 | 10.8 | 0.21 |
| 8 | gi|440901307 | Tropomyosin alpha-1 chain | 37.7 | 6.4 | 0.25 |
| 9 | gi|440904898 | Transgelin, partial | 23.0 | 35.8 | 0.27 |
| 10 | gi|114052094 | Calponin-1 | 33.4 | 36.7 | 0.31 |
| 11 | gi|440910551 | Platelet glycoprotein 4 | 53.4 | 4.2 | 0.31 |
| 12 | gi|440897546 | Phosphate carrier protein, mitochondrial, partial | 42.3 | 5.1 | 0.32 |
| 13 | gi|109891934 | RecName: Full=Isocitrate dehydrogenase | 51.1 | 6.9 | 0.34 |
| 14 | gi|440893758 | PDZ and LIM domain protein 3 | 39.9 | 4.1 | 0.35 |
| 15 | gi|440910545 | Tropomyosin alpha-1 chain | 37.4 | 9.2 | 0.36 |
| 16 | gi|115497074 | S-formylglutathione hydrolase | 32.3 | 2.5 | 0.36 |
| 17 | gi|440903063 | 2-oxoglutaratedehydrogenase, mitochondrial | 118.6 | 1.5 | 0.39 |
| 18 | gi|440907850 | Desmoplakin, partial | 329.7 | 0.5 | 0.42 |
| 19 | gi|440907068 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, partial | 111.4 | 2.1 | 0.42 |
| 20 | gi|440911054 | Desmin, partial | 46.3 | 31.2 | 0.43 |
| 21 | gi|78369436 | 3-ketoacyl-CoA thiolase, mitochondrial | 41.9 | 5.4 | 0.45 |
| 22 | gi|440909063 | Aspartate aminotransferase, cytoplasmic, partial | 47.2 | 2.4 | 0.47 |
| 23 | gi|431894354 | Myosin regulatory light polypeptide 9 | 20.2 | 39.2 | 0.47 |
| 24 | gi|426220158 | PREDICTED: tropomodulin-1 | 40.5 | 2.2 | 0.47 |
| 25 | gi|332634684 | Glutamate [NMDA] receptor subunit epsilon-3 precursor | 94.2 | 1.7 | 0.51 |
| 26 | gi|440896699 | Four and a half LIM domains protein 2, partial | 34.3 | 3.9 | 0.51 |
| 27 | gi|344253851 | Actin, gamma-enteric smooth muscle | 42.2 | 59.0 | 0.51 |
| 28 | gi|440904982 | Sodium-dependent phosphate transport protein 2B | 77.3 | 2.3 | 0.52 |
| 29 | gi|440897772 | Filamin-C | 293.4 | 2.1 | 0.52 |
| 30 | gi|440904421 | ATP-binding cassette sub-family G member 2 | 73.6 | 1.5 | 0.52 |
| 31 | gi|440897862 | Filamin-A | 283.1 | 18.1 | 0.53 |
| 32 | gi|440896802 | Myosin-11, partial | 176.4 | 4.3 | 0.55 |
| 33 | gi|440899469 | Citratesynthase, mitochondrial | 52.0 | 2.4 | 0.55 |
| 34 | gi|74354891 | GLUD1 protein | 57.4 | 1.8 | 0.56 |
| 35 | gi|120419518 | enigma protein | 50.8 | 4.8 | 0.56 |
| 36 | gi|440898241 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, partial | 80.5 | 1.8 | 0.56 |
| 37 | gi|440898951 | Creatine kinase B-type, partial | 43.2 | 18.2 | 0.58 |
| 38 | gi|444518229 | Myosin light chain 6B | 17.1 | 23.2 | 0.58 |
| 39 | gi|440912794 | Calcium-binding mitochondrial carrier protein Aralar1, partial | 73.9 | 1.5 | 0.59 |
| 40 | gi|440901372 | Fibrinogen alpha chain, partial | 86.6 | 12.8 | 0.59 |
| 41 | gi|114053019 | alpha-1B-glycoprotein precursor | 36.3 | 12.9 | 0.59 |
| 42 | gi|119888979 | PREDICTED: basement membrane-specific heparan sulfate proteoglycan core protein | 474.8 | 1.2 | 0.59 |
| 43 | gi|440909830 | Factor XIIa inhibitor, partial | 56.1 | 15.3 | 0.61 |
| 44 | gi|440902649 | Aspartate aminotransferase, mitochondrial | 47.9 | 2.3 | 0.61 |
| 45 | gi|440893207 | Myosin-7, partial | 223.1 | 4.9 | 0.61 |
| 46 | gi|77404217 | Phosphoglycerate mutase 1 | 28.9 | 10.2 | 0.63 |
| 47 | gi|296489917 | TPA: cellular repressor of E1A-stimulated genes | 17.5 | 22.9 | 0.64 |
| 48 | gi|139948177 | Cysteine and glycine-rich protein 1 | 21.4 | 25.9 | 0.64 |
| 49 | gi|410932519 | PREDICTED: uncharacterized protein LOC101077311 | 11.4 | 35.9 | 0.65 |
| 50 | gi|440901371 | Fibrinogen beta chain, partial | 56.7 | 19.8 | 0.65 |
* Relative abundance of proteins in HL yak milk versus TL yak milk.