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. 2022 Jan 31;14(3):749. doi: 10.3390/cancers14030749

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Gene expression profiling of three individual TRAMP tumors reveals distinct epithelial and neuroendocrine signatures for basal and luminal TRAMP tumor cells. (A) MA plot showing differentially expressed genes between basal (red) and luminal (blue) cells. Each dot represents a unique transcript. X-axis: average transcript expression, Y-axis: log2 difference in gene expression. (B) Barplots showing enriched biological processes in basal-specific (blue) and luminal-specific (red) genes ranked by −Log10 FDR.