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. Author manuscript; available in PMC: 2022 Apr 14.
Published in final edited form as: Nat Methods. 2021 Oct 14;18(11):1401–1408. doi: 10.1038/s41592-021-01285-2

Extended Data Fig. 2. Analysis of spike-evoked calcium responses in simulated calcium movies with ground truth.

Extended Data Fig. 2

(A) For the simulated movie in Supplementary Fig. 2, spike-triggered traces were generated at different levels of activity. Spikes were counted within 272 ms windows and used to sort calcium events. Left column corresponds to a single trial associated with one spiking event. Right column is the average of all associated trials. Traces were extracted from (B). For all neuronal compartments created in the field of view, the peak calcium spike amplitude was measured in ground truth data as well as in movies that went through DeepInterpolation and a gaussian kernel. Red line is the identity line. (C) Same plot as (B) except that the area under all calcium events was measured.