TABLE 4.

Association Between Histopathologic Characteristics and Imaging Features Derived from ¹⁸F-FDG PET Images

	Histologic grade				Lymph-vascular space invasion			Metastatic lymph nodes
Radiomic feature	1–2	3	P	Depth of invasion (mm)	No	Yes	P	No	Yes	P
SUVmax	12.1 ± 4.2	13.9 ± 3.0	0.3	R2 = 0.07	11.2 ± 3.2	13.7 ± 4.48	0.05	11.5 ± 4.2	13.0 ± 3.9	0.2
Local entropy	3.9 ± 0.11	3.9 ± 0.09	1	R2 = 0.10	3.9 ± 0.12	3.9 ± 0.10	0.6	3.9 ± 0.10	3.9 ± 0.11	0.4
Maximum 3D diameter	48.5 ± 19.4	44.6 ± 16.1	0.8	R2 = 0.08	47.6 ± 22.0	48.3 ± 15.0	0.7	46.9 ± 20.2	48.6 ± 18.0	0.9
Moran’s I	0.062 ± 0.018	0.057 ± 0.021	0.8	R2 = 0.013	0.059 ± 0.018	0.064 ± 0.020	0.6	0.062 ± 0.017	0.061 ± 0.020	0.9

R² indicates the coefficient of determination.