TABLE 1.

Performance of Reduced-Time-Point (TP) Methods for Clinical Cohort

		% Difference in TIA
Patient	Kidney	Mono 1 TP Madsen	Bi 1 TP Madsen	1 TP Hanscheid*	1 TP MM	2 TP MM	2 TP Mono
1	Left	4.1 [0.88]	−3.1 [0.99]	−3.0	−1.7 [0.99]	−2.4 [0.99]	−3.1 [0.89]
	Right	2.1 [0.88]	−5.0 [0.99]	−4.9	−3.0 [0.99]	−3.1 [0.99]	−4.0 [0.89]
2	Left	0.7 [0.89]	−4.0 [0.99]	1.8	−2.7 0.99]	−0.9 [0.99]	−1.1 [0.90]
	Right	0.9 [0.89]	−3.8 [0.99]	2.0	−2.5 [0.99]	−0.7 [0.99]	−0.9 [0.90]
3	Left	1.5 [0.93]	−3.3 [0.96]	2.3	−1.8 [0.97]	5.5 [0.98]	5.4 [0.93]
	Right	−18.4 [0.92]	−22.3 [0.93]	−17.7	−15.9 [0.95]	4.7 [0.98]	2.6 [0.93]
4	Left	−6.2 [0.93]	−10.3 [0.96]	−4.3	−7.3 [0.97]	−0.5 [0.98]	−1.7 [0.93]
	Right	−6.9 [0.93]	−11.0 [0.96]	−5.1	−8.0 [0.97]	−1.2 [0.98]	−2.4 [0.93]
6	Left	0.3 [0.82]	−4.2 [0.97]	1.7	−4.4 [0.95]	−6.1 [0.96]	−4.1 [0.85]
	Right	2.0 [0.81]	−2.6 [0.97]	3.4	−3.0 [0.95]	−4.9 [0.97]	−1.9 [0.84]
7	Left	4.7 [0.90]	0.2 [0.98]	6.8	0.5 [0.98]	−1.4 [0.99]	0.7 [0.92]
	Right	5.8 [0.87]	1.2 [0.99]	7.9	1.2 [0.99]	−1.2 [0.99]	2.3 [0.90]
8	Left	0.7 [0.91]	−6.6 [0.99]	−7.7	−0.5 [0.99]	2.8 [0.99]	−0.1 [0.91]
	Right	−1.4 [0.91]	−8.5 [0.99]	−9.6	−1.3 [0.99]	2.6 [0.99]	−0.6 [0.91]
9	Left	9.2 [0.86]	1.2 [0.99]	0.0	1.1 [0.99]	−2.6 [0.99]	−3.0 [0.88]
	Right	15.1 [0.84]	6.7 [0.99]	5.4	4.2 [0.99]	−1.3 [0.98]	−0.5 [0.87]
10	Left	1.2 [0.64]	−3.1 [0.86]	3.3	−2.8 [0.84]	−11.1 [0.98]	310.7 [0.77]
	Right	−4.9 [0.62]	−9.0 [0.86]	−2.9	−8.7 [0.84]	−16.5 [0.97]	278.0 [0.76]

^*Hanscheid approximation provides TIA and not a curve fit.

Patient 5 was excluded from analysis due to not having a ∼96 H measurement. $\text{\% Difference}=100\text{*}\frac{{\text{TIA}}_{\text{Estimated}}-{\text{TIA}}_{\text{Gold Standard}}}{{\text{TIA}}_{\text{Gold Standard}}}$.

MM = mixed model. Mono and Bi refer to monoexponential and biexponential, respectively.

Data in brackets are R² of curve fit.