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. 2022 Feb 8;14(3):850. doi: 10.3390/cancers14030850

Table 4.

Correlation analysis between survivor subgroups and median allele frequency rates of pathogenic KRAS and TP53 mutations. A Mann–Whitney U test was used to test for significance (p-value < 0.05 indicates significance).

OS OS DFS DFS
<4 Years ≥4 Years p-Value <2 Years ≥2 Years p-Value
n = 31 n = 8 n = 32 n = 7
Median (range)
allele
frequency rate
KRAS
14%
(2–32%)
11%
(4–30%)
0.368 14.5%
(2–32%)
11.0%
(4–13%)
0.042
Median (range)
allele
frequency rate
TP53
17%
(10–54%)
11%
(2–17%)
0.017 17%
(2–54%)
12%
(10–14%)
0.054

DFS: disease-free survival; OS: overall survival.