Table 1.
Age, years | |
Mean | 67 |
Range | 44–88 |
Sex, n.(%) | |
Male | 46 (64%) |
Female | 26 (36%) |
Line of therapy | |
1st | 72 (100%) |
Treatment received | |
CT plus Bev CT alone |
50 (69%) 22 (31%) |
Location of primary tumor | |
Left | 48 (66%) |
Right | 24 (34%) |
Site of metastasis | |
Single organ | 26 (36%) |
Multi-organ | 46 (64%) |
Liver | 62 (86%) |
Peritoneum | 12 (17%) |
Lymph-node | 10 (14%) |
Lung | 6 (8%) |
Histology | |
Adenocarcinoma | 72 (100%) |
RAS tissue/plasma baseline | |
Mutated KRAS G12D KRAS G12V KRAS G12A KRAS G12R/S KRAS G12C KRAS Q61 KRAS A146T KRAS G13D NRAS G12D NRAS G12C NRAS Q61R NRAS A146T BRAF V600E |
72(100%) 19 (26%) 16 (22%) 5 (7%) 2 (3%) 6 (8%) 5 (7%) 5 (7%) 7 (10%) 3 (4%) 1(1%) 1 (1%) 1(1%) 1(1%) |
CT: chemotherapy; Bev: Bevacizumab.