ALC |
alcoholism |
ALT |
alternative lengthening of telomeres |
AUT |
autism |
BP |
gene sets related to biological processes; part of Gene Ontology (GO) data base |
BPD |
bipolar disorder |
bp |
base pairs (DNA nucleobases) |
CD4 & 8 |
cluster of differentiation 4 and 8; co-receptors of T cells |
CG |
cytosin and guanine; see CpG |
Chr |
chromosome |
CIMP |
CpG island methylator phenotype in colorectal cancer |
CpG island |
genomic regions with high frequency of cytosine and guanine |
CRC |
colorectal cancer |
CTCF |
transcriptional repressor; also known as 11-zinc finger protein |
DKC1 |
dyskerin pseudouridine synthase 1 |
DN |
down-regulation in gene set or pathway analyses |
DNA |
deoxyribonucleic acid |
Dnmt |
DNA methylation maintenance methyltransferases |
DPR |
major depression |
E- |
expression- (profiles, SOM, spots, or portrait) |
E1–E8 |
expression subtypes of LGG |
exSOM |
extension SOM transfer learning approach |
EZH1 |
histone-lysine N-methyltransferase |
GBM |
glioblastoma WHO grade IV |
GEO |
Gene Expression Omnibus repository for Transcriptome data |
GCIMP |
glioma CpG island hypermethylation phenotype; associated with IHD mutation |
GPCR
|
G-protein-coupled receptors |
GO |
Gene Ontology database |
GSZ |
gene set Z-score |
H3K |
methylation of lysine side chains (histone subunit 3) at positions 4, 9, 27 or 36 |
Het |
heterochromatin |
HetRpts |
heterochromatin repeats |
HR |
homologous recombination |
IDH
|
isocitrate dehydrogenase |
IDH-A |
IDH-mutated astrocytoma-like subset of gliomas with chromosome 1p19q intact |
IDH-mut |
gliomas carrying mutation in IDH genes |
IDH-O |
IDH-mutated oligodendroglioma-like subset of gliomas with chromosome 1p19q intact |
IDH-wt |
gliomas with wildtype IDH genes |
KEGG |
Kyoto Encyclopedia of Genes and Genomes; database of cellular pathways |
KTM |
lysine methyltransferases |
KDM |
lysine demethylases |
LGG |
lower-grade diffuse gliomas (WHO grade II and III) |
M- |
methylation- (profiles, SOM, spots, or portrait) |
M1-M6 |
methylation subtypes of LGG |
MES |
mesenchymal subtype of gliobalstomas according to Verhaak et al. (2010) |
MHC |
Major Histocompatibility Complex |
NL |
neuronal-like subset of gliomas according to Verhaak et al. (2010) |
NPC |
neuronal progenitors |
PA |
pilocytic astrozytoma |
PCM |
pairwise correlation map |
PRC1&2 |
polycomb repressive complex 1 and 2 |
PSF |
pathway signal flow algorithm |
RA |
Reactome cellular pathway database |
RC |
repressive complexes |
RepPRC |
repressed polycomb states |
RepPCWk |
repressed polycomb states, weak |
SCZ |
schizophrenia |
SOM |
Self-organizing map |
TEL |
telomerase |
TERT |
telomerase reverse transcriptase |
Tet1–Tet3 |
DNA demethylases |
TM |
telomere length maintenance |
Treg |
regulatory T cell |
TssA/TssP |
active/poised gene promoters |
Tx |
transcribed genes |
UP |
up-regulation in gene set or pathway analyses |
WHSC1 |
histone-lysine N-methyltransferase |
ZNF |
zinc finger proteins |