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. 2022 Jan 19;19(3):1085. doi: 10.3390/ijerph19031085

Table 3.

Predictors of virological non-suppression among patients living with HIV under dolutegravir (n = 305) *.

N Crude Adjusted
OR 95% CI p-Value OR 95% CI p-Value
Age
18–24 29 1 1
25–34 87 0.43 0.17–1.09 0.076 0.33 0.12–0.93 0.035
35–49 133 0.88 0.37–2.05 0.762 0.69 0.25–1.85 0.455
50 and + 56 0.70 0.26–1.83 0.461 0.53 0.17–1.61 0.259
Sex
Female 219 1 1
Male 86 0.89 0.50–1.57 0.688 0.94 0.47–1.87 0.854
Education
None/Primary 195 1 1
Secondary/Tertiary 110 0.93 0.55–1.58 0.802 1.29 0.67–2.48 0.446
Marital status
Living alone 180 1 1
In Union 125 1.22 0.74–2.04 0.435 1.28 0.68–2.42 0.447
Ethnic group
Nilotic 157 1 1
Bantu 72 1.59 0.85–2.99 0.147 180 0.79–3.34 0.122
Semi-Bantu 58 1.50 0.76–2.96 0.243 1.51 0.67–2.93 0.284
Sudanese 18 4.52 1.66–12.34 0.003 4.19 1.43–12.68 0.012
Residence
Rural 17 1 1
Urban 288 0.56 0.16–1.99 0.368 0.62 0.14–2.76 0.527
Creatinine
Normal 233 1 1
Abnormal 72 2.43 1.39–4.25 0.002 2.32 1.22–4.43 0.010
Stage
I and II 159 1 1
III and IV 146 1.74 1.04–2.89 0.034 1.86 1.01–3.43 0.047
Viral load at baseline
<1000 copies/mL 224 1 1
≥1000 copies/mL 81 2.39 1.39–4.12 0.002 3.41 1.64–7.08 0.001
Tobacco consumption
No 239 1 1
Yes 66 0.82 0.43–1.54 0.541 0.79 0.35–1.78 0.565
Status of treatment at baseline
Under ART before inclusion 220 1 1
Self-reported naïve patients with baseline VL < 50 copies/mL 52 1.24 0.521 0.64–2.40 1.44 0.66–3.12 0.361
Self-reported naïve patients with baseline VL ≥ 50 copies/mL 33 1.05 0.912 0.46–2.38 0.32 0.11–0.92 0.034
Exposition time under DTG-based regimen in months
6 to 7 98 1 1
8 to 9 49 0.46 0.18–1.15 0.099 0.71 0.26–1.96 0.510
10 to 12 158 1.28 0.73–2.24 0.384 1.22 0.64–2.33 0.554

*: Those who had viral load results at 6–12 months.