Table 3.
Case No. | Sex | Age | Primary Location | Tissue Origin | Grade | Preoperative Therapy | SSTR2 Immunoreactivity | Treatment | Response to SSA | SD, CR = Positive PD = Negative | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Volante Score | IRS | DIA * | ||||||||||
1 | M | 63 | midgut | primary site | G1 | TS1, Octreotide | 2 | 4 | 769 | Octreotide, UFT | CR | positive |
2 | F | 60 | hindgut | primary site | G2 | Not done | 2 | 6 | 1492 | Lanreotide | SD | positive |
3 | M | 55 | midgut | primary site | G2 | Not done | 3 | 12 | 1741 | Lanreotide | SD | positive |
4 | M | 61 | hindgut | primary site | G2 | Octreotide | 1 | 0 | 163 | Octreotide | SD | positive |
5 | F | 45 | hindgut | primary site | G1 | Octreotide, Lanreotide | 2 | 2 | 1075 | Octreotide, Lanreotide | SD | positive |
6 | M | 65 | hindgut | primary site | G2 | Not done | 2 | 4 | 898 | Octreotide, Lanreotide | SD | positive |
7 | M | 48 | hindgut | metastatic site (liver) | G2 | Octreotide, Lanreotide | 2 | 2 | 830 | Octreotide, Lanreotide | PD | negative |
8 | M | 72 | midgut | metastatic site (liver) | G2 | Octreotide, Lanreotide | 2 | 4 | 731 | Octreotide, Lanreotide | PD | negative |
9 | M | 61 | foregut | primary site | G2 | Not done | 2 | 12 | 2379 | Octreotide | PD | negative |
10 | M | 73 | foregut | metastatic site (liver) | G2 | Not done | 1 | 0 | 215 | Lanreotide | PD | negative |
11 | M | 74 | midgut | primary site | G1 | Not done | 2 | 8 | 1240 | Lanreotide | SD | positive |
12 | F | 65 | foregut | metastatic site (liver) | G1 | Octreotide | 2 | 8 | 1467 | Octreotide | SD | positive |
13 | F | 67 | midgut | primary site | G1 | Octreotide, Everolimus | 2 | 2 | 967 | Octreotide | SD | positive |
14 | F | 71 | hindgut | primary site | G2 | Not done | 2 | 4 | 1027 | 5FU, CDDP, Octreotide | SD | positive |
* Round down after the decimal point. Abbreviations: IRS—immunoreactive score; DIA—digital image analysis; SSA—somatostatin analogue; UFT—uracil-tegafur; 5FU—5-fluorouracile; CDDP—cisplatin; SD—stable disease; CR—complete response; PD—progressive disease.