Table 2.
Clinicopathological characteristics of patients with ovarian cancer according to P1 tumor engraftment status.
| Successful Engraftment | ||||||
|---|---|---|---|---|---|---|
| Variables | Case | Successful Engraftment | Failed Engraftment | p Value | Tumor Growth Rate a | p Value d |
| All, n | 130 | 61 | 69 | |||
| Age (year) a | 52.12 ± 12.22 | 52.08 ± 12.51 | 52.16 ± 12.05 | 0.9706 b | ||
| Pre CA-125 level (U/mL) a | 942.7 ± 2315 | 1442 ± 3124 | 475.4 ± 942.7 | 0.0216 b | ||
| Borderline tumors, n | 10 | 2 | 8 | |||
| Histology, n (%) | 1.0000 c | |||||
| Serous | 2 (20.00) | 0 (0.0) | 2 (25.00) | N/A | N/A | |
| Mucinous | 8 (80.00) | 2 (100) | 6 (75.00) | 167.55 ± 102.2 | ||
| Malignant tumors, n | 120 | 59 | 61 | |||
| Epithelial ovarian cancer, n | 112 | 54 | 58 | |||
| Histology, n (%) | 0.0389 c | |||||
| Serous | 68 (60.71) | 39 (72.22) | 29 (50.00) | 300.9 ± 248.3 | reference | |
| Clear | 17 (15.18) | 6 (11.11) | 11 (18.97) | 395.4 ± 383.1 | 0.6088 | |
| Endometrioid | 7 (6.25) | 2 (3.70) | 5 (8.62) | 90.28 ± 2.653 | <0.0001 | |
| Mucinous | 12 (10.71) | 2 (3.70) | 10 (17.24) | 373.5 ± 322.0 | 0.807 | |
| MMMT | 7 (6.25) | 5 (9.26) | 2 (3.45) | 632.7 ± 696.4 | 0.059 | |
| Brenner | 1 (0.89) | 0 (0.0) | 1 (1.72) | N/A | N/A | |
| Stage, n (%) | 0.0004 c | |||||
| I | 27 (24.11) | 5 (9.26) | 22 (37.93) | 112.6 ± 53.89 | reference | |
| II/III/IV/Recurrent | 85 (75.89) | 49 (90.74) | 36 (62.07) | 359.3 ± 335.1 | 0.0002 | |
| Grade, n (%) | 0.0073 c | |||||
| 1 | 8 (7.14) | 0 (0.0) | 8 (13.79) | N/A | ||
| 2 | 10 (8.93) | 7 (12.96) | 3 (5.17) | 316.6 ± 166.8 | reference | |
| 3 | 70 (62.50) | 37 (68.52) | 33 (56.90) | 332.5 ± 287.1 | 0.2044 | |
| Unknown | 24 (21.43) | 10 (18.52) | 14 (24.14) | 443.7 ± 521.4 | N/A | |
| Non-Epithelial ovarian cancer, n | 8 | 5 | 3 | |||
| Histology, n (%) | 0.2369 c | |||||
| Sex cord-stromal | 1 (12.50) | 0 (0.0) | 1 (33.33) | N/A | N/A | |
| Germ cell | 5 (62.50) | 3 (60.00) | 2 (66.67) | 84.12 ± 106.3 | ||
| Metastatic | 2 (25.00) | 2 (40.00) | 0 (0.0) | N/A | ||
| Stage, n (%) | 0.1964 c | |||||
| I | 5 (62.50) | 2 (40.00) | 3 (10.00) | 159.25 | N/A | |
| II/III/IV/Recurrent | 3 (37.50) | 3 (60.00) | 0 (0.0) | 8.98 | ||
a Values are mean ± standard derivation. b Unpaired t-test for success and failure. c Chi-square test or Fisher’s exact test values for success and failure. d Unpaired t-test with Welch’s correction. Unknown data was excluded in calculation of p value. N/A, not applicable.