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Alterations in the urea cycle in 15-day-old DJ-1β mutant flies. (a) Schematic diagram of the urea cycle. Fumarate is a final metabolite that can enter the TCA cycle. (b) Expression levels of selected enzymes of the urea cycle, arginase (Arg) and argininosuccinate lyase (ArgL). Error bars show s.d. from four independent experiments (*, p < 0.05).
