Table 1.

Regulation of endocrine FGFs by stress signaling.

FGFs	Regulator	Stimuli	Refs
FGF15/19	ATF4	ER stress	[122]
	ATF4 1	Oxidative stress	[125]
	ATF4 1	Amino acid deprivation	[125]
FGF21	ATF4	ER stress	[125,126,127]
	XBP-1	ER stress	[128]
	ATF4	Oxidative stress	[125,126]
	ATF4	Amino acid deprivation	[125,129,130,131,132,133]
	NRF2 2	Oxidative stress	[134,135,136,137,138]
	ATF4	Mitochondrial stress	[130,139]
	ATF2	Cold stress	[55,140]
	PPARα	Fasting	[60,65,70]
	GR	Fasting	[71,72]
	CREBH	Fasting	[73,74]
	ChREBP	High carbohydrate	[141,142,143,144,145,146,147]
	PPARγ	Obesity/feeding	[56,148,149]
FGF23	-	-	-

¹ Only in vitro. ² Both positive and negative regulations have been reported.