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Discrepancy of the effectively present culture conditions between the medium supernatant and the interstitial fluid of fibroblasts and keratinocytes in a collagen fleece. Online monitoring within the monitoring platform of (A) oxygen, (B) pH, (C) glucose, and (D) lactate concentrations in the medium supernatant (red line,) and the interstitial fluid for fibroblasts (blue line) and keratinocytes (green line).
