Table 3.
Antifungal activity (inhibition zone and MIC mg/mL) of mastic extracts before and after liposome encapsulation.
Mastic Extract | Liposome Type | Candida albicans | Candida tropicalis | Candida glabrata |
---|---|---|---|---|
Total mastic gum | 14/0.73 | 16/0.56 | 19/0.32 | |
Free AMGE | 10/1.10 | 11/0.98 | 13/0.78 | |
Free NMGE | 12/1.25 | 13/1.00 | 130.85 | |
Liposome + AMGE | EI | 8/1.90 | 9/1.88 | 10/1.81 |
Liposome + NMGE | EI | 9/1.98 | 9/2.00 | 10/1.87 |
5-Flucytosine | 21/1 × 10−3 | 22/1 × 10−3 | 25/0.5 × 10−3 | |
AmphotericinΒ | 22/1 × 10−3 | 23/0.5 × 10−3 | 23/0.4 × 10−3 |
AMGE: acidic mastic gum extract; NMGE: neutral mastic gum extract; EI: Ethanol Injection.